Claustrophobia is a fear of tight or enclosed spaces, often brought on by trauma within a confined space, or extensive and frequent connections to the higher planes through a familiarity with Necromancy.
With the availability of Necromancy, death doesn't have to mean the end.
A dangerous but curable condition, Imperium Toxicity is caused by Imperium levels in excess of what the subject's metabolism can safely manage.
The Shattered cease to exist, their souls too destroyed for resurrection or the Afterlife.
The Soulbound are those bound to an object within the mortal plane. The duration of the binding, the soul's abilities while bound, and their choice in whether or not to remain in this condition all depend upon the type of binding spell cast.
Vampirism is an infectious viral disease, resulting in higher iron consumption requirements, slowed metabolism, increased Imperium production, and improved healing and immune responses in its victims.